Double Defense Set

Limited edition Double Defense Set featuring NEW Silymarin C F and Physical Fusion UV Defense SPF 50

$166.00

SkinCeuticals Double Defense Set is an ideal regimen for full-spectrum protection against premature aging caused by UV, ozone, and diesel engine exhaust. 

Product Details

  • Silymarin C F

    • 15% L-ascorbic Acid: Lauded for its superior antioxidant benefits, this highly potent form of pure vitamin C helps neutralize free radicals and protect against oxidative stress while providing visible anti-aging benefits.
    • 0.5% Silymarin: Powerful plant-based antioxidant derived from milk thistle that helps prevent oil oxidation and provides antioxidant protection against free radicals.
    • 0.5% Ferulic Acid: A plant-based antioxidant, ferulic acid neutralizes free radicals and enhances the antioxidant benefits and stability of vitamin C.
    • 0.5% Salicylic Acid: A beta-hydroxy acid provides effective exfoliation, refines pores, and helps reduce the formation of blemishes.


  • Physical Fusion UV Defense SPF 50

    • 5% Zinc Oxide (Z-Cote®): This microfine zinc oxide is a mineral filter that reflects sun rays to provide broad spectrum protection against UVA and UVB rays. The particle size and distribution characteristics spread evenly and provide a non-whitening effect on skin.
    • 6% Titanium Dioxide: Microfine titanium dioxide is a mineral SPF filter that acts as a weightless reflector on skin to protect against UVA and UVB rays.
    • Artemia Salina: This plankton extract helps boost skin’s natural defenses and resistance to UV- and heat-induced stress.
    • Translucent Color Spheres: Iron oxide spheres that act as a color-infused technology to enhance natural skin tone and boost radiance while providing a universal tint for most skin tones.

In the morning after cleansing and toning, apply 4-5 drops of Silymarin C F to a dry face, neck, and chest before other skincare products. Complete your regimen with Physical Fusion UV Defense SPF 50. When used together, SkinCeuticals antioxidants and broad spectrum sunscreens provide protection against visible aging caused by environmental aggressors.

Silymarin CF is a breakthrough vitamin C serum for oily and blemish-prone skin that combines 0.5% silymarin (milk thistle extract), 15% l-ascorbic acid, 0.5% ferulic acid and 0.5% salicylic acid to help prevent oil oxidation that can lead to breakouts, and visible signs of aging. This oil-free formula is clinically demonstrated to reduce oil oxidation by up to 76%, as well as reduce oiliness, refine skin texture, and visibly improve skin clarity and fine lines. 

Physical Fusion UV Defense SPF 50 is a weightless fluid that combines 100% mineral filters with translucent color spheres for effective broad spectrum UVA/UVB protection and an even, radiant finish. This high protection zinc oxide sunscreen also contains artemia salina, a plankton extract known to increase skin’s resistance to UV- and heat-induced stress.

  • Sheer, tinted sunscreen adapts to most skin tones without a white cast 
  • Water resistant for up to 40 minutes
  • Boosts radiance for a more even, luminous complexion
  • Helps boost skin’s natural defenses to environmental stress
  • Paraben-free and fragrance-free; non-comedogenic
  • Ideal for all skin types, even very sensitive skin

 Oily, Combination

Acne, Aging

Acne, Aging

Key Benefits

  • Provides advanced antioxidant protection from environmental aggressors 
  • Helps prevent oil oxidation that can lead to breakouts
  • Reduces oiliness
  • Minimizes pore appearance and refines skin texture
  • Improves skin clarity, radiance, and uneven skin tone
  • Improves the appearance of fine lines